In short: Under the supervision of an appropriately specialized surgeon the lady will be sedated but conscious, the top of her skull removed and the "mopes" (what is the origin of this term?) will line up to ejaculate upon her exposed brain with all of her reactions documented if any. Multicamera shoot.
Admittedly this idea comes from the Ridley Scott Hannibal Lecter movie, the scene with Ray Liotta, which I only recently saw for the first time. Turd film with a few great moments. You could convincingly argue that Scott only directed it so he could stage and shoot that scene with the outdoor opera performance, which is heartmeltingly beautiful. And loved Gary Oldman.