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Good points jrv. They would ideally have simulated gravity on the real trip. Otherwise, there are any number of physiological problems to be overcome. Many areas of the body are adversely effected by weightlessness . . . from the heart, to the bone, to the bones
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This can be achieved a couple of ways without needing any new sort of artificial gravity technology.
1. have a rotating spaceship (would need a pretty big radius to feel right.)
2. Accelerate at a constant 9.8 ms^2 to the halfway point, flip around and decelerate at -9.8 ms^2 the rest of the way.
(This would require an absurd amount of fuel with current propulsion technology. Would make for a fast journey though.)
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