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"Talk about bad timing!

Tony Romo called it quits with Jessica Simpson the night before her 29th birthday, People.com reports.

"She is heartbroken," says the source. "She loves Tony. But it's been difficult lately. He's busy with his career and she's getting ready to shoot her show (The Price of Beauty). They decided to part ways."

Speculation of the couple’s recent split arose when the Dallas Cowboys quarterback and 14 of his friends partied at Hollywood hotspot MyHouse on Friday night – Simpson's 29th birthday – without the birthday girl.

This isn’t the first break-up for the couple, who began dating in 2007.

Romo reportedly dumped Simpson last May, but was able to patch things up in time to attend sister Ashlee Simpson’s wedding a few days later.

The couple’s split may be good news to Cowboys fans as Simpson, who wore a pink No. 9 jersey to games, was thought to be bad luck to Romo’s football performance. The singer was even nicknamed “Yoko Romo.”

Simpson is said to have planned a Barbie and Ken-themed birthday party for July 10, however no such event happened.

"Barbie party didn't happen, but I turned 29 and feel like I am on top of the world yelling I LOVE GETTING OLDER!" she wrote on Twitter.

Although a suddenly single Simpson may be heartbroken, the singer is staying positive.

"Everyone needs to know that hope floats ... grab the strings and pull it back to you," she tweeted.

Simpson’s rep had no comment. Romo's rep could not be reached for comment."

Cowboys suck, Romo sucks. Jessica Simpson is hot, but her stupidity and her father are going to drive away every celebrity she dates. Her dad was pocketing $$ informing paparazzi where her and Romo would be going. Oh, and she'll never date "down", daddy wouldn't let her.