I have a friend with the HIVvy...and other than the EXPENSIVE meds he acts and feels just like any joe blow. Actually i must say he is actually a happier person now. But Im sure that's not going to be the case with everyone. It made him realize what's important in life, and what just garbage. He used to be a tortured soul, but now he is pretty normal and happy. Hes had it for 7 years and supposedly his viral load is almost undectable. HIV meds have come a LONG way.