when you go to vegas, you will probably want to check out the crown and anchor, its an english pub that is open 24hours and you can watch aussie and english sports while drinking. its pretty good. here is a good schedule of the popular nightclubs to hit

Monday - anywhere in Mandalay Bay, right now its Mix
Tuesday - Pure at Caesars Palace
Wednesday - anywhere at MGM (Studio 54 or Tabu)
Thursday - Rain at the Palms
Friday - Body English at Hard Rock
Tryst at the Wynn Resort
Saturday - Pure at Caesars Palace
Body English at Hard Rock
Jet at Mirage
Sunday - Lite at Bellagio

also, Sunday afternoon is the pool party at the Hard Rock called Rehab...its fucking incredible...picture ALL of the strippers in vegas, except in bikinis and partying by the pool during the day. good times

also, for strip clubs.....i wouldn't stray outside of the Crazy Horse II or Spearmint Rhino, anything else is hit or miss, those 2 are always the bomb.

and there you go.......i lived in vegas for a couple of years and worked in those clubs, so this is pretty dead on.