This thread reminds me of when I saw the movie "The Other Sister". When they were about to have sex, I wondered what it would be like for them and if they had any fucking clue what they were doing.
With that said I know nothing about Down Syndrome, but I have heard stuff about Autism. Some of them aren't capable of ever being potty trained.
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"Nature already created the perfect dishwasher....its called a woman." - Fiend