The only problem(s) I ever had with drugs was:
(1) Certain times Not being able to find any
(2) running out too soon (happens a lot)
(3) People (usually chicks) raiding my stash(s)...if they had just asked nicely it wouldn't be on this list...
(3a) Drug sniffing rodents, like mice, who have arthritis and need pain medicine...
(4) Leaving the bottle in my coat or pants pocket and the fucking thing gets drycleaned. The pills usually melt or dissolve outright...all I can do is lick the bottle